Peptide Profiles

In 1977, two Swiss researchers did something beautifully weird: they took blood from a sleeping rabbit, filtered out the small molecules, and injected them into an awake rabbit. The awake rabbit fell into deep delta-wave sleep. Something in the blood was carrying a sleep signal. They isolated it, sequenced it, and named it delta sleep-inducing […]

There’s an enzyme in your fat cells called NNMT. Its job, essentially, is to slow down your metabolism — it degrades a methyl donor that cells need to produce NAD+, the coenzyme that powers cellular energy production. More NNMT activity → less NAD+ → slower metabolism → more fat storage. It’s a brake pedal on […]

Three amino acids. That’s it. Lysine-Proline-Valine — a tripeptide so small it barely qualifies as a peptide at all. But KPV has generated outsized research interest because this tiny fragment, snipped from the tail end of alpha-MSH, packs anti-inflammatory activity that works through mechanisms most conventional anti-inflammatory compounds don’t touch. Here’s what the published research […]

Tesamorelin is a modified full-length GHRH analog with enhanced DPP-4 resistance. Review of preclinical and published research on visceral adipose tissue, hepatic fat, body composition, and cognitive effects.

Sermorelin and CJC-1295 are synthetic GHRH analogs that stimulate growth hormone release through the endogenous pathway. Review of mechanisms, half-life differences, synergy with GHS compounds, and preclinical applications.

MOTS-c is a mitochondrial-derived peptide that activates AMPK and regulates metabolic homeostasis. Review of its discovery, nuclear translocation mechanism, exercise-mimetic properties, and aging research.

PT-141 is a selective melanocortin-4 receptor agonist derived from Melanotan-II research. Review of preclinical evidence on MC4R mechanisms, central nervous system pathways, and reproductive research.

AOD9604 is a synthetic fragment of human growth hormone (amino acids 177-191) studied for selective lipolytic activity without growth-promoting effects. Review of preclinical research on mechanisms and metabolic findings.

NAD+ is a coenzyme central to cellular metabolism, DNA repair, and aging. This review covers the biochemistry, age-related decline, and key preclinical findings from published research.

Epithalon is a synthetic tetrapeptide studied for its effects on telomerase activity, telomere elongation, and aging biomarkers. Review of the peer-reviewed literature from three decades of investigation.