Metabolic Research

MOTS-C

Mitochondrial-Derived Peptide

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Brief Description

Mitochondrial-derived peptide encoded within the 12S rRNA gene — one of the first identified signaling peptides originating from mitochondrial DNA. MOTS-C can translocate to the nucleus and regulate gene expression in response to metabolic stress, activating AMPK and influencing the folate-methionine cycle. Research areas include exercise physiology, insulin sensitivity, age-related metabolic decline, and mitochondrial-nuclear communication. For research use only — not for human consumption.

Batch Documentation
Current batch
Batch B002 · 99.043% HPLC
Janoshik Analytical · HPLC purity analysis + mass spectrometry identity confirmation
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Prior batches
Batch B001
March 2026 - 99.42% HPLC
Verify →
Research & library
Research review
Scientific background, literature, and compound context
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COA library
Browse current and supporting batch documentation
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Scope limit: COAs document analytical testing for research materials. They are not medical-use, diagnostic, or treatment claims.
Batch 002 Transparency Note
Transparency update

Due to recent supply chain and international shipping disruptions, some Batch 002 inventory may include vials produced at different points within our supplier’s production cycle. As a result, researchers may notice minor packaging variations, including differences in vial caps.

These products were sourced from the same established manufacturers we have worked with for ongoing quality and third-party testing. That said, we want to be transparent that Batch 002 may not represent a single uninterrupted production run.

We are already working with our suppliers to strengthen batch-control, packaging, and documentation protocols before Batch 003.

Current batch by strength
10mg
Batch 002
20mg
Batch 002
If you need a specific production run, match the selected strength to the batch listed here before opening the COA link.
Compound Specifications
CAS
1627580-64-6
MW
2174.64 g/mol
Formula
C101H152N28O25S2
Purity
99.043%
Storage & Handling
Lyophilized: Stable at room temperature; freezer (−20°C) recommended for long-term storage
Reconstituted: 2–8°C, use within 30 days
Solvent: Bacteriostatic water — if solution appears turbid, add trace acetic acid (0.6%)
Why do some peptides need acetic acid? →
For research use only — not for human consumption
MOTS-C
MOTS-C
$52.00 $80.00Price range: $52.00 through $80.00 SAVE 20%

Additional information

Weight 0.94 oz
Strength

10mg, 20mg